Searchable abstracts of presentations at key conferences in endocrinology

ea0067o39 | Oral Presentations | EYES2019

The role of microRNAs and its targeted genes in development of ACTH-dependent hypercortisolism

Khandaeva PM , Belaya ZE , Nikitin AG , Solodovnikov AS , Lutsenko AS

Objective: To analyze the role of miRNAs previously found to be differentially expressed in patients with ACTH-dependent Cushing syndrome (CS).Materials and methods: We analyzed putative targets of three microRNAs, which were previously found to be differentially expressed in ACTH-dependent CS patients: miR-16-5p, miR-145-5p, miR-7g-5p. We used TargetScan (TS) and DIANA tools (DT) predictions.Results: We found different plasma expr...